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WHO WE ARE WHAT WE ARE ASKING WHAT WE ARE DOING WHAT WE WOULD LIKE TO DO PICTURE GALLERY MOVIES
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Novikov, D.V., Kireev, I., Belmont, A.S., High-pressure treatment of polytene chromosomes improves structural resolution, Nat. Methods 4:48-485 (2007) Belmont, A.S., Mitotic chromosome structure and condensation, Curr. Opin. Cell Biol. 18:632-638 (2006) Chuang, C., Carpenter, A.E., Fuchsova, B., Johnson, T., de Lanerolle, P., Belmont, A.S., Long- range directional movement of an interphase chromosome site. Curr. Biol. 16:825-831 (2006) Brink, M.C., van der Velden, Y., de Leeuw, W., Mateos-Langerak, J., Belmont, A.S., van Driel, R., Verschure, P.J., Truncated HP1 lacking a functional chromodomain induces heterochromatinization upon in vivo targeting, Histochem Cell Biol. 125:53-61 (2006) Chuang, CH. and A.S. Belmont, Close encounters between active genes in the nucleus. Genome Biol. 6:237 (2005) Levi, V., Ruan, Q., Plutz, M., Belmont, A.S., Gratton, E., Chromatin dynamics in interphase cells revealed by tracking in a two-photon exicitation microscope, Biophysical J. 89(6): 4275-85 (2005) Verschure, P.J., van der Kraan, I., de Leeuw, W., van der Vlag, J., Carpenter, A.E., Belmont, A.S., van Driel, R., In vivo HP1 targeting causes large-scale chromatin condensation and enhanced lysine methylation, Mol. Cell Biol., 25:4552-64 (2005) Carpenter, A.E., Memedula, S., Plutz, M.J., A.S. Belmont, Common effects of acidic activators on large-scale chromatin structure and transcription, Mol. Cell. Biol. 25: 958-68 (2005) Chen, D., Belmont, A.S., Huang, S., Upstream binding factor association induces large-scale chromatin decondensation, PNAS 101: 15106-11 (2004) Dietzel, S., Zolghadr, K., Hepperger, C., A.S. Belmont, Differential large-scale chromatin compaction and intranuclear positioning of transcribed versus non-transcribed transgene arrays containing beta-globin regulatory sequences, J. Cell Sci. 117: 4603-4614 (2004) Kireeva, N., Lakonishok, M., Kireev, I., Hirano, T., A.S. Belmont, Visualization of Early Chromosome Condensation: A Hierarchical Folding, Axial Glue Model of Chromosome Structure, J. Cell Biol. 166: 775-785 (2004) Nye, A.C., Ashouri, A., A.S. Belmont, Automated microscopy identifies estrogen receptor subdomains with large-scale chromatin structure unfolding activity, Cytometry 58A(2):157-166 (2004) Carpenter, A.E. and A.S. Belmont, Direct visualization of transcription factor induced chromatin remodeling and cofactor recruitment in vivo, in "Methods in Enzymology: Chromatin and Chromatin Remodeling Enzymes", Academic Press, Vol 375:366-381 (2004) Strukov, Y.G. and A.S. Belmont, Development of Mammalian Cell Lines with Lac Operator Tagged Chromosomes, in "Live Cell Imaging: A Laboratory Manual", CSHL press, 2004 Strukov, Y.G., Wang, Y., A.S. Belmont, Engineered chromosome regions with altered sequence composition demonstrate hierarchical large-scale folding within metaphase chromosomes, J. Cell Biol. 162:23-35 (2003) Belmont, A.S., Dynamics of chromatin, proteins, and bodies within the cell nucleus, Curr. Opin. Cell Biol. 15:1-7 (2003) Memedula, S. and A.S. Belmont, Sequential recruitment of HAT and SWI/SNF components to condensed chromatin by VP16, Curr. Biol. 13: 241-246 (2003) Li, Y., Danzer, J.R., Alvarez, P., Belmont, A.S., L.L. Wallrath, Effects of tethering HP1 to euchromatic regions of the Drosophila genome, Development 130:1817-1824 (2003) Belmont, A.S, Mitotic chromosome scaffold structure: new approaches to an old controversy, PNAS 99:15855-15857 (2002) Vazquez, J., Belmont, A.S., J.W. Sedat, The dynamics of homologous chromosome pairing during male Drosophila meiosis, Curr. Biol. 12:1473-1483 (2002) Nye, A.C., Rajendran, R.R., Stenoien, D.L., Mancini, M.A., Katzenellenbogen, B.S., Belmont, A.S., Alterations of large-scale chromatin structure by the estrogen receptor, Molecular and Cellular Biology, Mol. Cell. Biol. 22: 3437-3449 (2002) Ye, Q., Hu, Y-F., Zhong, H., Nye, A.C.*, Belmont, A.S.*, R. Li, BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations, J. Cell Biol. . 155:911-921 (2001) Stenoien, D.L., Nye, A.C., Mancini, M.G., Patel, K., Dutertre, M., O'Malley, B., Smith, C.L., Belmont, A.S., M.A. Mancini, Ligand-mediated assembly and altered dynamics of estrogen receptor-SRC-1 complexes in living cells, Molecular and Cellular Biology, 21: 4404-4412 (2001) Vazquez, J., Belmont, A.S., J.W. Sedat, Multiple regimes of constrained chromosome
motion are regulated during interphase in Drosophila, Current Biology, 11:
1227-1239 (2001) A.S. Belmont, Visualizing chromosome dynamics with GFP, Trends in Cell Biology, 6: 250-257 (2001) Dietzel, S. and Belmont, A.S. (2001) "Reproducible but dynamic positioning of DNA within chromosomes during mitosis," Nature Cell Biology, 3:767-770. Tumbar, T. and Belmont, A.S. (2001) "Interphase movements of a DNA chromosome region modulated by VP16 transcriptional activator," Nature Cell Biology 3:134-139. Tsukamoto, Hashiguchi, N., Janicki, S., Tumbar, T., Belmont, A.S., and Spector, D.L. (2000) "Visualization of gene activity in living cells," Nature Cell Biology 2:871-878. Mahy, N.L., Bickmore, W.A., Tumbar, T., and Belmont, A.S. (2000) "Linking large-scale chromatin structure with nuclear function," In: Chromatin Structure and Gene Expression. S.C.R. Elgin and J.L. Workman, editors. Oxford University Press. Belmont, A.S., Dietzel, S., Ney, A.C., Strukov, Y.G., and Tumbar, T. (1999) "Large-scale chromatin structure and function," Curr. Opin. Cell Biol. 11:307-11. Tumbar, T., Sudlow, G., and Belmont, A.S. (1999) "Large-scale chromatin unfolding and remondeling induced by VPI6 acidic activation domain," J. Cell Biol. 145:1341-54. Belmont, A.S., Li, G., Sudlow, G., Robinett, C., Visualization of large-scale chromatin structure and dynamics using the lac operator / lac repressor reporter system, Methods Cell Biol.58: 203-222 (1998) Belmont, A.S., A.F. Straight, In vivo visualization of chromosomes using lac operator / repressor binding, (1998) Trends in Cell Biol. 8: 121-124 Li, G., Sudlow, G., A.S. Belmont, Interphase cell cycle dynamics of a late replicating, heterochromatic HSR: precise choreography of condensation/decondensation and nuclear positioning, J. Cell Biol. 140: 975-989 (1998) A.S. Belmont, Nuclear ultrastructure: Transmission electron microscopy and image analysis, Methods Cell Biol. 53: 99-124 (1998) A.S. Belmont, Large-scale Chromatin Structure, in "Genome Structure and Function", NATO Advanced Study Institute, Kluwer Acad. Pub., 261-278 (1997) Marshall, W.F., Straight, A., Marko, J.F., Swedlow, J., Dernburg, A., Belmont, A., Murray, A.W., Agard, D.A., J.W. Sedat,, Interphase chromosomes undergo constrained diffusional motion in living cells, Curr. Biol. 7: 930-939 (1997) C.D. Webb, A. Teleman, S. Gordon, A. Straight, A. Belmont, D.C. Lin, A.D. Grossman, A. Wright, R. Losick, Bipolar localization of the replication origin regions of chromosomes in vegetative and sporulating cells in B. subtilis, Cell 88: 667-674 (1997) J. Minshull, A. Straight, A. Rudner, A. Dernburg, A. Belmont, A.W. Murray, Protein phosphatase 2A regulates MPF activity and sister chromatid cohesion in budding yeast, Curr. Biol. 6: 1609-1620 (1996) A.F. Straight, A.S. Belmont, C.C. Robinett, A.W. Murray, GFP tagging of budding yeast chromosomes reveals that protein-protein interactions can mediate sister chromatid cohesion, Curr. Biol. 6: 1599-1608 (1996) C. Robinett, A. Straight, G. Li, C. Willhelm, G. Sudlow, A. Murray, A. S. Belmont, In vivo localization of DNA sequences and visualization of large-scale chromatin organization using lac operator/repressor recognition, J. Cell Biol. 135: 1685-1700 (1996) J. Pixton, A. S. Belmont, Newvision: a program for interactive navigation and analysis of multiple 3-D data sets using coordinated virtual cameras, J. Struct. Biol. 116: 77-85 (1996) R. Brady, J. Pixton, G. Baxtor, P. Moran, C. S. Potter, B. Carragher, A. Belmont, Crumbs: a virtual environment tracking tool for biological imaging, in Proc. IEEE Symp., 1995 Biomedical Visualization, pp. 18-25, Editors, Murray Loew, Nahum Gershon, IEEE Comp. Soc. Press, Los Alamitos, CA (1995) A. Delaney, A. S. Belmont, Deblurring of high tilt projections for EM tomography, Ultramicroscopy 56: 319-335 (1994) A. S. Belmont, K. Bruce, G. Li, Three-dimensional visualization of G1 chromosomes: a folded, twisted, supercoiled chromonema model of interphase chromatid structure, J. Cell Biol. 127: 287-302 (1994) A. S. Belmont, Y. Zhai, A. Thilenius, Lamin B distribution and association with peripheral chromatin revealed by optical sectioning and EM tomography, J. Cell Biol. 123:1671-1685 (1993)
Complete Lab Publications:
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