Olga G. Nalbandov Symposium

Membrane Proteins: Experimental and Computational Approaches to

Understanding Cellular Function

Program

Saturday May 4

7:30 a.m. Continental Breakfast

8:15 a.m. Welcome and Opening Remarks

Session I Chair: Zan Schulten

8:30 a.m. Axel Brunger (Stanford)

"Biophysical and Structural Insights into the Mechanism of Synaptic Vesicle Fusion"

9:15 a.m. Horst Vogel (EPFL)

"Probing the Function of Neuro-Receptors by Micro- and Nanotechnology"

10:00 a.m. Peter Agre (Johns Hopkins)

"Aquaporin Water Channels - Physiology and Pathophysiology"

10:45 a.m. Coffee

Session II Chair: Tony Crofts

11:15 a.m. Robert Stroud (UCSF)

"What Does the Structure Tell us about Selectivity of Aquaporins and

Aquaglyceroporins?"

12:00 p.m. Klaus Schulten (UIUC)

"Membrane Channels in Action"

12:45 p.m. Lunch

Session III Chair: Steve Sligar

2:00 p.m. Yoshinori Fujiyoshi (Kyoto, Japan)

"Structure and Function of Channels"

2:45 p.m. Marilyn Gunner (CCNY)

"Using Calculation to Identify Motifs for Stabilizing Charges within

Membrane Proteins."

3:30 p.m. Petra Fromme (Berlin)

"Structure and Function of Photosystem I and II"

4:15 p.m. Coffee

Session IV Chair: Bob Gennis

4:45 p.m. Hartmut Michel (Frankfurt)

"Cytochrome c Oxidase: Structure and Coupling of Electron Transfer

to Proton Pumping"

5:30 p.m. Ben de Kruijff (Utrecht)

"The Specificity of Protein-Lipid Interactions and their Significance for

Membrane Organization and Function"

6:15 p.m. Gunnar von Heijne (Stockholm)

"Membrane Proteins: From Bioinformatics to Large-scale Topology Mapping"

7:00 p.m. Open Reception/Buffet Beckman Atrium

Sunday May 5

7:30 a.m. Continental Breakfast

Session V Chair: Eric Jakobsson

8:30 a.m. Stephen White (UC Irvine)

"How Membranes Shape Protein Structure"

9:15 a.m. Joao Morais Cabral (Yale)

"Ion Permeation Through a Potassium Channel"

10:00 a.m. Mark Sansom (Oxford)

"Molecular Dynamics Simulations of Ion Channels and Related Proteins:

KcsA and OmpA"

10:45 a.m. Coffee

Session VI Chair: John Whitmarsh

11:15 a.m. Dieter Oesterhelt (Martinsried)

"Chloride Transport and Bioenergetics in Halophilic Archaea"

12:00 p.m. James Bowie (UCLA)

"Stabilizing Membrane Proteins"

12:45 p.m. End