James B. NardiResearch ScientistPhD, 1975, Harvard UniversityPhone: 217-333-6590 |
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Nardi is interested in the cell-cell and cell-substratum interactions that mold insect tissues. He addresses questions at the tissue, cell, and molecular levels about factors involved in organizing insect cells into their precise patterns in space and time. These questions have focused on how cell surface and extracellular matrix molecules mediate directional movements and rearrangement of cells during development of insect tissues. Most recently he has been studying lacunin, a large extracellular protein with many protease inhibitor domains. He also is collaborating with Hugh Robertson on studies of the molecular basis of olfaction in insects, particularly using Manduca sexta as a model system.
Nardi, J. B. 1981. Induction of invagination in insect epithelium: A paradigm for embryonic invagination. Science 214, 564-566.
Nardi, J. B. 1983. Neuronal pathfinding in developing wings of the moth Manduca sexta. Dev. Biol. 95, 163-174.
Nardi, J. B. and S. M. Magee-Adams 1986. Formation of scale spacing patterns in a moth wing. I. Epithelial feet may mediate cell rearrangement. Dev. Biol. 116, 278-290.
Nardi, J. B. 1990. Expression of a surface epitope on cells that link branches in the tracheal network of Manduca sexta. Development 110, 681-688.
Nardi, J. B. 1992. Dynamic expression of a cell surface protein during rearrangement of epithelial cells in the Manduca wing monolayer. Dev. Biol. 152, 161-171.
Nardi, J. B. 1993. Modulated expression of a surface epitope on migrating germ cells of Manduca sexta embryos. Development 118, 967-975.
Nardi, J. B. 1994. Rearrangement of epithelial cell types in an insect wing monolayer is accompanied by differential expression of a cell surface protein. Dev. Dynamics 199, 315-325.
Nardi, J. B. and E. G. Cattani 1995. Expression of a cell surface protein during morphogenesis of the reproductive system in Manduca sexta embryos. Both moths and mammals have an indifferent stage of genital differentiation. Roux Arch. Dev. Biol. 205, 21-30.
Nardi, J. B., P. F. Dowd and R. J. Bartelt 1996. Fine structure of cells specialized for secretion of aggregation pheromone in a nitidulid beetle Carpophilus freemani (Coleoptera: Nitidulidae). Tissue & Cell 28, 43-52.
Chen, C. L., D. L. Lampe, H. M. Robertson and J. B. Nardi 1997. Neuroglian is expressed on cells destined to form the prothoracic glands of Manduca embryos as they segregate from surrounding cells and rearrange during morphogenesis. Dev. Biol. 181, 1-13.
Nardi, J. B. and E. A. Ujhelyi 1998. Remodeling of neural, glial, and tracheal cell populations in the developing Manduca wing. Cell Tissue Res., in press.
