MCB 493
Cellular Microbiology and Disease
School of Molecular & Cellular Biology
University of Illinois at Urbana-Champaign
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Classes

Class

Date

Lecture

HTML File

PDF File

Module 1: Fundamentals of Host Pathogen Interactions (Chapters 1-2).

1

1/16/07

Intro. to Cellular Microbiology; Fundamental Principles of Infectious Diseases - I; Pathogens of the Week #1

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PDF

2

1/18/07

Fundamental Principles of Infectious Diseases - II

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3

1/23/07

Sites of Bacterial Colonization and Attachment: Templates for Pathogen Modulation-I ; Pathogens of the Week #2

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4

1/25/07

Sites of Bacterial Colonization and Attachment: Templates for Pathogen Modulation-II; (Quiz #1: classes 1-3)

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5

1/30/07

Strategies of bacterial pathogens-I; Pathogens of the Week #3

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6

2/1/07

Strategies of bacterial pathogens-I

 

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Module 2: Pathogen Modulation of Host Cell Signaling (Chapters 3, 13-16).

7

2/6/07

Signal Transduction - I; Pathogens of the Week #4

 

PDF

8

2/8/07

Test # 1 (Classes 1-6)          

 

 

9

2/13/07

Signal Transduction - II; Pathogens of the Week #5

 

 

10

2/15/07

Toxins – I        Introduction, Type III secretion; Type IV secretion

 

DOC

11

2/20/07

Toxins - II; Pathogens of the Week #6

 

PDF

12

2/22/07

Toxins – III (Quiz #2; classes 1-11)

 

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Module 3: Pathogen Manipulation of host cells via adhesion and adhesion-based signaling (Chapters 4-7).

13

2/27/07

Extracellular Matrix and Host Cell Surfaces: Potential Sites of Pathogen Interactions; Pathogens of the Week #7

 

PDF

14

3/1/07

Bacterial Adherence to Cell Surfaces and Extracellular Matrix

 

PDF

15

3/6/07

Bacterial Adherence to Cell Surfaces and Extracellular Matrix

 

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16

3/8/07

Test #2 (Classes 1-14)  

 

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17

3/13/07

Bacterial signaling to host cells through adhesion molecules and lipid rafts; Pathogens of the Week #9        

 

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Paper #1

 

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Module 4: Pathogen manipulation of host cells: establishment of intracellular lifestyles. (Chapters 8-10).

18

3/15/07

Host cell membrane structure and dynamics - I

 

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Paper #2

 

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19

3/27/07

Host cell membrane structure and dynamics - II; Pathogens of the Week #10

 

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Paper #3

 

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20

3/29/07

Membrane traffic in the endocytic pathway of eukaryotic cells (Quiz #3; classes 1-19)

 

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21

4/03/07

Routes of invasion and selection of an intracellular niche; Pathogens of the Week #11

 

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22

4/05/07

Selection of an intracellular niche and modulation of intracellular compartments

 

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Paper #4

 

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Paper #5

 

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Module 5: Pathogen manipulation of host cell cytoskeleton. (Chapters 11-12).

23

4/10/07

Actin assembly and kinetics; Pathogens of the Week #12

 

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Paper #6

 

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24

4/12/07

Test #3 (Classes 1-22)

 

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25

4/17/07

Modulation of actin dynamics by actin-binding proteins; Pathogens of the Week #13

 

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26

4/19/07

Manipulating the cytoskeleton to promote invasion

 

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    Paper #7  
    Paper #8  

27

4/24/07

Intracellular motility and intracellular spread; Pathogens of the Week #14

 

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Paper #9

 

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Module 6: Pathogen manipulation of host cells viability. (Chapter 17).

28

4/26/07

Pathogen manipulation of cell death mechanisms

 

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    Paper #10  

29

4/31/07

Pathogen manipulation of autophagy; Pathogens of the Week #15

 

PDF

30

5/02/07

Pathogen manipulation of the cell cycle

 

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31

TBA

Test #4 (Classes 1-30)

 

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